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The genetic algorithm described below was run using the PyPy 5.4.1 interpreter, while all other scripts were run using the standard Python 2.7.11 interpreter. RNAFold (89) was used to compute secondary structures and folding energies for…

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To localize incorporation of AB61 in cells and to further investigate the mechanisms of incorporation into the DNA, we have employed structural analogue of AB61, compound PNH404 (Fig.

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